Genomics Resources at UNM

Analytical and Translational Genomics Shared Resource

The Analytical and Translational Genomics (ATG) Shared Resource is the genomics and next-generation sequencing core facility in the UNM Cancer Center. ATG was originally the Keck-UNM Genomics Resource (KUGR), founded in 2000 and focused on microarray technologies. In the last few years ATG has transitioned primarily to next-generation sequencing technologies using the Ion Proton and Ion Torrent PGM platforms. ATG staff include a research technician and an expert data analyst with expertise analyzing genomics data sets with software such as GeneSpring, CLC Bio and R/Bioconductor. ATG also has a fully equipped and upgraded Affymetrix system with two automated fluidics stations and a scanner with autoloader, an Agilent BioAnalyzer, a Nanodrop droplet spectrophotometer, a Qubit fluorometer and Qiagen Qiacube robot for automated sample processing and related equipment for performing genomics, gene expression and microarray experiments. ATG is supported by the State of New Mexico, the UNM Cancer Center, the UNM Clinical Translational Science Center and by user fees.

Bioinformatics Expertise

Bioinformatics support in the UNM Cancer Center is provided by an integrated team including experts in genomics, biostatistics, database management and computational approaches. This team was recently established to address the sophisticated data analysis needs required by next-generation DNA sequencing based assays and approaches. The bioinformatics team currently includes Y. Guo (Bioinformatics Shared Reource), H. Kang and L. Luo (Biostatistics Shared Resource) and K. Brayer (ATG) and the team is led by S.Ness. The bioinformatics team members are in the CRF building.

Computational Facilities

The UNM Center for Advanced Research Computing (CARC), directed by Dr. Susan R. Atlas, provides parallel supercomputing, high-speed networking, large-scale storage and visualization capabilities to the entire UNM research community and houses a total of about 5 Tflops/sec (peak) of computing power and just under 400 TB of storage, including a new state-of-the-art 281 TB multi-tier, RAID storage system (integrated by Hewlett-Packard). The system is designed to scale to 16 PB. Several large memory supercomputers (e.g. Nano; Pequena) connect to the storage system via a secure high-speed network. This internal network serving data to the CARC supercomputers is further connected to the central campus Core and thus to the UNM Cancer Research Facility. It provides redundant switching capabilities for high availability in connecting the storage array to CARC parallel supercomputers.